For some schizophrenics, who have not responded to other drugs, clozaril has been deemed effective.
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a blood thinner such as warfarin, coumadin , jantoven methotrexate trexall ropinirole requip clozapine clozaril , fazaclo odt a non-steroidal anti-inflammatory drug nsaid .
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clozaril may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects.
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clozaril, an atypical antipsychotic drug, is a tricyclic dibenzodiazepine derivative, 8-chloro-11- 4-methyl-1-piperazinyl -5 h -dibenzo b,e 1,4 diazepine.
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adverse events observed in association with the use of clozaril in clinical trials at an incidence of greater than 5 were central nervous system complaints, including drowsiness sedation, dizziness vertigo, headache and tremor; autonomic nervous system complaints, including salivation, sweating, dry mouth and visual disturbances; cardiovascular findings, including tachycardia, hypotension and syncope; and gastrointestinal complaints, including constipation and nausea; and fever.
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